
Fig. 1. Schematic representations of the domains of a subgroup A thrombospondin
subunit and the recombinant protein units of TSP-1 and TSP-2. Nomenclature:
NTD or N, N-terminal domain; o, oligomerisation sequence; C, procollagen
module, P, type 1 (properdin) repeat; E, type 2 (EGF-like) repeat; Ca, type 3
repeat/C-terminal globule; CTD, C-terminal globule; Del, deleted. The smaller
protein units are designated by the domains they contain. To avoid lengthy
terminology, the largest multidomain units are designated by the portions
deleted. In the text, each unit is also designated (1) or (2) to indicate
whether the protein unit is derived from TSP-1 or TSP-2, respectively.