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Fig. 6. Comparison of the effects of (a) Gö 6976 and (b) Gö 6850 on metabolic stress-stimulated hexose transport. Clone 9 cells in triplicate culture dishes were treated with or without the indicated concentrations of inhibitors for 45 minutes. During the last 30 minutes of this period, they were treated with (azide) or without (basal) 5 mM sodium azide. Uptake of (a) [3H]3-O-methyl-D-glucose or (b) [3H]2-deoxy-D-glucose was then measured as described in the Materials and Methods. Results shown are the means±s.e.m.; *this value is significantly different (P<0.05) from the azide-stimulated uptake rate in the absence of the inhibitor.





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