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Fig. 6. Variable characteristics of spontaneous Ca2+ signals in RyR3-expressing cells. A and B illustrate the considerable variability of spontaneous Ca2+ signals in two RyR3-expressing cells. The traces in Aa and Ba depict the Ca2+ changes in the regions along the line scan images marked by the arrows. Panel C depicts the effect of 100 µM ryanodine treatment on spontaneous Ca2+-release activity in a single RyR3-expressing cell.





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