Fig. 3. Cas promotes Fak-independent Y. pseudotuberculosis uptake. (A)
Fak-/- MEFs were transfected with the designated amounts of a
plasmid encoding Cas. Uptake levels for each condition were compared by ANOVA
to the level observed for mock-transfected cells. The data presented were
obtained from 11 independent experiments. Uptake of YP17/pVector into
mock-transfected cells averaged 35%. Error bars represent limits at a 95%
confidence level. (B) Representative Cas immunoblot showing Cas expression in
lysates from Fak-/- MEFs transfected with the designated amounts of
DNA Cas.
