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The dystrophin-associated protein complex

The dystrophin-associated protein complex (DAPC) is an assembly of proteins that links the extracellular matrix (ECM), sarcolemma and actin cytoskeleton in skeletal and cardiac muscle. Mutations in its components are linked to a variety of muscle disorders, including Duchenne muscular dystrophy, and this reflects its critical role in preservation of muscle integrity. In Cell Science at a Glance on p. 2801, Kay Davies and co-workers provide a model of the DAPC, surveying its main components and the diseases with which they are associated.

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The dystrophin-associated protein complex

Jeffrey Ehmsen, Ellen Poon, and Kay Davies
JCS 2002 115: 2801-2803. [Full Text]  

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This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in JCS Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Search for Related Content Social Bookmarking                         What's this?