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Fig. 3. Mutant opsin inclusions have the characteristics of an aggresome. Mutant
opsin (P23H-GFP) colocalised with c-myctagged ubiquitin when co-transfected in
COS-7 cells. The P23H-GFP opsin inclusions led to the disruption of the
intermediate filament network (Vimentin). The cytoplasmic chaperone Hsc70 was
recruited to the P23H-GFP inclusions. Bar, 10 µm.
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