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Fig. 2. TIF1ß is targeted to centromeric heterochromatin in ES-derived
neurons. A and D show representative phase-contrast photomicrographs of
undifferentiated ES cells growing on a layer of feeder cells in the presence
of LIF (control) and ES-derived neurons taken 4 days after plating of the
RA-treated embryoid bodies in defined medium (RA), respectively. Confocal
images of single optical sections through the nucleus of undifferentiated and
differentiated cells are shown. B and E show the Hoechst DNA staining, and C
and F, the TIF1ß staining. Bars, 100 µm for (A) and (D) or 5 µm for
others.
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