Fig. 1. Cloning and sequencing of human LTBP-3. (A) A schematic presentation of the obtained cDNA and of some of the recognition sites of the restriction enzymes, which were used in the process of cloning. (B) The nucleotide and deduced amino-acid sequence of human LTBP-3. Nucleotide numbering starts from the proposed upstream translation initiation codon. Exon-intron boundaries are marked with vertical lines and EGF-like repeats are shaded with gray. 8-Cys repeats and the hybrid domains are indicated by patterns of eight circled cysteines. An alternative splice site of hL3+EGF is marked with an asterisk (^*). Specified arrows are used to show the 5' coding ends of phL3 and phL3+ATG cDNA expression constructs.

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