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Fig. 2. (A) The continuum model of a 1D cytogel strip representing the lamellipod (see Appendix). (B) The finite element model of the lamellipod. The lamellipod is triangulated so that each node represents a mass of cytoskeleton contained in the surrounding (Voronoi) polygon. (C) Detail of a finite element consisting of an elastic element in parallel with a tensile element. The dashpot with damping coefficient µ connected to the substratum accounts for the viscous dissipation associated with making and breaking attachments as well as the dissipation associated with cytoskeleton-fluid friction.





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