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Fig. 6. The RQC domain deletion mutant of WRN localizes outside the nucleoli. (A) Schematic representation of the generation of the WRN{Delta}853-1089 (I853L). Numbers correspond to amino acid sequences. (B) HeLa cells were transfected with EGFP-WRN{Delta}853-1089 (I853L) and analyzed as described in Fig. 1A,B. One representative picture is shown.





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