Fig. 10. Alignment of tail sequences of Acanthamoeba, Dictyostelium and chicken smooth muscle myosins reveals limited similarities. Sequences beginning with the invariant Pro that defines the head/tail junction (Korn, 2000) were aligned by the default mode of the PC version of Clustal X (Thompson et al., 1997). Amino acids that occur at the same positions in all three myosins are in red, those that occur only in Acanthamoeba and Dictyostelium myosins are in blue, and those that occur in smooth muscle and Dictyostelium myosins are in green. The region of highest similarity in the three myosins and the corresponding region of chicken skeletal muscle myosin are enlarged at the bottom of the figure. Amino acids in skeletal muscle myosin that are the same as those in the corresponding positions of the three other myosins are in red, those that are the same as in Acanthamoeba and Dictyostelium myosins are in blue, those that are the same as in smooth muscle and Dictyostelium myosins are in green and those that are the same only in skeletal and Dictyostelium myosins are in purple. The GenBank accession numbers are: Acanthamoeba myosin, P05659; Dictyostelium myosin, A26655; smooth muscle myosin, P01587; skeletal muscle myosin, P13538.

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