Fig. 2. Mat1 is essential for mitotic germ cells. (A) Hematoxylin eosin (H&E) stained sections of control and mutant testis at 3 weeks (P21) and at 6 weeks (P42) of age. The asterisk marks an example of an abnormal seminiferous tubule where spermatogonia and spermatocytes are absent. The arrow marks pycnotic spermatogonia. (B) Macroscopic view (top panel) and H&E stained histological sections (middle panel 10x, lower panel 400x) of male reproductive organs from control and mutant animals at 3 months of age (P100). Abbreviations: Se, Sertoli cells; sp, spermatids; sv, seminal vesicle; bl, urinary bladder; de, ductus epididymis; ce, cauda epididymis; te, testis.

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