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Fig. 4. Substitution of ß-catenin by plakoglobin in ß-catenin-null mutant
keratinocytes in the TritonX-100-soluble fraction (same as in
Fig. 3). Co-precipitation was
done with E-cadherin, plakoglobin or desmoglein3 antibodies. The same western
blots were sequentially developed with the indicated antibodies. Note that
clearly more plakoglobin associated with E-cadherin in
ß-catenin-/- cells than in ß-catenin+/- or
ß-catenin+/+ cells. Dsg3, desmoglein3; E-cad, E-cadherin;
-cat, -catenin; ß-cat, ß-catenin; PG, plakoglobin;
Pph, plakophilin.
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