Fig. 6. Extranuclear hnRNP A2 and KSRP are differentially localized. (A) A cultured oligodendrocyte showing the presence of KSRP (C2742 antibody, red) and hnRNP A2 (green) in the nucleus and processes. In the cell body the relative level of hnRNP A2 is higher. The two asterisks mark what appear to be adjacent cells. (B) A magnified view of a process of the cell from multiple merged optical sections. Distinct populations of granules containing KSRP (arrowheads) or hnRNP A2 (arrows) are evident in the oligodendrocyte processes. (C) A histogram showing the fluorescence ratios [red/(red + green); see Materials and Methods] of granules in four cells (excluding the cell shown in A) double-labeled for hnRNP A2 (green) and KSRP (red). Bars, A, 10 µm, B, 2.5 µm.

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