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Fig. 10. S13A cells remain abnormally elongate and continue to translocate, albeit
at reduced velocity, at the deduced peak and in the deduced back of a
self-generated natural wave of cAMP. (A,B) Velocity plots of a representative
JH10 cell and a representative S13A-1 cell in respective homogeneous
aggregation territories responding to three natural sequential waves of cAMP.
The phases of the wave (A+B, C+D) are deduced from the velocity plots
described previously (Wessels et al.,
1992). (C,D) Centroid tracks of the representative JH10 cell and
representative S13A cell through the three successive natural waves (1,2,3) in
which the deduced peak plus back portions (phases C plus D) are boxed. Arrows
point in the direction of the interpreted aggregation centers. (E,F) Amplified
centroid tracks through one wave and associated cell morphologies. Similar
results were obtained for nine additional S13A-1 cells and ten S13A-2 cells
analyzed in a similar fashion.