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Fig. 1. Comparison of the deduced amino-acid sequences of Tom70 from rats and N. crassa. (A) The sequences of rats and N. crassa Tom70 were aligned using the Multiple Sequence program (DNASIS). The amino-acid residues conserved among species were shaded, TMDs were boxed and TPR motifs were underlined and numbered. TPR motifs were searched for using the Protein Families database alignment program (Pfam). (B) Comparison of hydropathy profiles of Tom70 from rats and N. crassa using the Kyte and Doolittle algorithm at a span setting of 10 amino-acid residues.





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