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Fig. 8. A model illustrating Syt III function in endosomal trafficking. According
to this model, in control cells (A) Syt III regulates the formation of the
endocytic recycling compartment (ERC) and the delivery to this compartment
from the early endosome (EE) and the immature granule (ISG) during the process
of granule maturation. In the RBL-Syt III- cells (B), suppression
of Syt III inhibits the formation of and delivery to ERC from both the EE and
the ISG.
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