Fig. 6. Overproduction of C-PAK affects E. histolytica motility. The mean speed (µm/s) and the trajectory diameter (µm), representing the largest distance between two arbitrary points of the total trajectory of each amoeba (control and C-PAK+ •), were plotted. When the trajectory diameter was greater than the size of an amoeba (25 µm), we concluded that the parasite migrated, and when it was below 25 µm, the parasite was considered to be unable to migrate. Note that 80% of the analysed C-PAK+ population did not migrate. Velocities of amoeba from the control strain reached 0.9 µm/s. Each plot is a compilation of three distinct experiments.

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