Fig. 4. Histogram of cell elongations for cells cultured on substrates patterned with 70 nm wide ridges and 600 nm deep grooves, on a 400 nm pitch and for cells cultured on smooth silicon oxide substrates. On the patterned substrates more than 80% of the cells with elongations higher than 2 were aligned along the substrate patterns. There was no correlation between cell elongation and the percentage of cells with orientation angles less than 10° on the smooth substrates.

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