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Fig. 1. His3-CPS is a reporter for mutations that block the MVB pathway. Schematic
diagram of His3-CPS sorting in wild-type cells (A) and in mutant cells
defective in either MVB cargo selection or MVB vesicle formation (B). (C) The
growth of wild-type cells and a representative class E vps mutant,
vps4, that have been streaked onto medium lacking supplemental
histidine.
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