Fig. 7. Dynamics of GFP-SMN and YFP-coilin through mitosis. (A) Three-dimensional projections of serial sections from a time series of line GFP-SMNE10.3 from prophase through to telophase. Mitotic Cajal bodies (MCBs) are arrowed. (B) GFP-SMNE10.3 through telophase. Large numbers of small SMN-positive bodies (arrows) appear in late telophase. (C) GFP-SMNE10.3 from telophase to G1. The SMN-positive bodies disappear as GFP-SMN begins to accumulate in nuclear Cajal bodies (arrows). (D) Three-dimensional projections of serial sections from a time series of line YFP-coilinE1.1.1 from prophase through to telophase. Mitotic Cajal bodies are arrowed. (E) YFP-coilinE1.1.1 in G1. Coilin-positive Cajal bodies are seen to form either distant from (arrow) or near to (arrowhead) nascent nucleoli.

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