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Journal of Cell Science 116, e1104 (2003)
Copyright © 2003 The Company of Biologists Limited

In this issue

Interpreting the histone code


Histone tails are subject to a variety of post-translational modifications. The various methylations, acetylations and phosphorylations constitute the so-called `histone code' and are an important means of epigenetic regulation. In Cell Science at a Glance, Thomas Jenuwein and co-workers explain how this code is interpreted, focusing on histone lysine methylation and its role in silencing, transcriptional activation, X inactivation and senescence (see p. 2117 + poster).


Related articles in JCS:

An epigenetic road map for histone lysine methylation
Monika Lachner, Roderick J. O'Sullivan, and Thomas Jenuwein
JCS 2003 116: 2117-2124. [Full Text]  




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