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Interpreting the histone code

Histone tails are subject to a variety of post-translational modifications. The various methylations, acetylations and phosphorylations constitute the so-called `histone code' and are an important means of epigenetic regulation. In Cell Science at a Glance, Thomas Jenuwein and co-workers explain how this code is interpreted, focusing on histone lysine methylation and its role in silencing, transcriptional activation, X inactivation and senescence (see p. 2117 + poster).

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Related articles in JCS:

An epigenetic road map for histone lysine methylation

Monika Lachner, Roderick J. O'Sullivan, and Thomas Jenuwein
JCS 2003 116: 2117-2124. [Full Text]  

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in JCS Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content Social Bookmarking                         What's this?