Fig. 6. Peripherin association with microtubules and motors. Peripherin particles and squiggles are closely associated with microtubules (MT) in the growth cone of a PC12 cell in DM for 4 hours. (A-D) Double label immunofluorescence. (A) peripherin (red); (B) microtubules (green); (C) overlay. D is a magnified view of the peripheral region of the growth cone shown in C. (E) Overlay of a double-labeled immunofluorescence preparation showing the association (yellow) between peripherin particles and squiggles (red) and kinesin (green). (F) Overlay of double label immunofluorescence preparation showing the association (yellow) between peripherin (red) and dynein IC (green). Bars, 2 µm.

Return to article