Fig. 6. AMPA-induced [Ca²⁺]_c increases. 100 µM AMPA was applied at each point indicated by an arrowhead for 12 seconds. (A) Nifedipine (10 µM) inhibited the 100 µM AMPA-elicited [Ca²⁺]_c rises (n=4). In the Ca²⁺-free solution, AMPA did not rise [Ca²⁺]_c at all (n=3). (B) 1 µM -agatoxin IVA (n=2; b) but not 1 µM -conotoxin GVIA (n=4; a) slightly inhibited the AMPA-induced [Ca²⁺]_c rises. (C) Summary of the above data. Nifedipine, 67.7±12.5%, n=4; -conotoxin GVIA, 95.0±0.5%, n=4; -agatoxin IVA, 88.8±0.5%, n=2; *Significant difference (paired student t-test, P<0.05).

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