Fig. 9. Inhibition of [Ca²⁺]_c rises by antagonists for AMPA/kainate, NMDA, and metabotropic glutamate receptors at different glutamate concentrations in SNc dopamine neurons. The black curves indicate the glutamate-induced [Ca²⁺]_c rises at the indicated concentrations, and the red curves indicate the glutamate-induced [Ca²⁺]_c rises in the presence of 30 µM CNQX (A), 50 µM AP-5 (B), 100 µM CPCCOEt (C), respectively. (D) Different contributions of AMPA/kainate, NMDA, and metabotropic glutamate receptors to the [Ca²⁺]_c rises according to glutamate concentrations. Each point was calculated by analysis of the data from 4-20 cells. All the solutions contain 1 µM glycine.

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