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Fig. 7. Possible mitotic and meiotic cohesin complexes in yeast and mammals. In
budding yeast, one of the mitotic cohesin subunits, Scc1p, is replaced by
Rec8p in meiosis. In mammals, by contrast, two types of cohesin complex exist
in mitosis; their components are SMC1
, SMC3, Rad21 and either one of
SA1 and SA2. In meiosis, three proteins, SMC1, Rad21 and SA1/SA2, are
likely to be replaced by SMC1ß, Rec8 and SA3/SAX (unidentified meiotic SA
homolog) in the meiotic cohesin complexes, respectively.
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