Fig. 1. Deficient epithelial tissue formation of HaCaT cells in organotypic co-cultures. Epidermal tissue morphology of organotypic co-cultures of normal keratinocytes (NEK) or HaCaT cells grown on collagen type I gels containing 2x10⁵/ml postmitotic fibroblasts throughout a 12-day-culture period (H and E staining; same magnification in all panels; bar, 100 µm).

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