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Fig. 1. ADAM12 expression in adipose tissues. (A-D) ADAM12 expression was demonstrated by immunostaining (arrows) in white adipose tissue from a normal mouse (A), in a human lipoma (B), in mouse brown and white adipose tissue (C), and in a human hibernoma (D). (E) The expression of ADAM12 mRNA in mouse abdominal (Ab)-, epididymal (Ep)-white adipose tissue (WAT) and brown adipose tissue (BAT), was shown by northern blot analysis. Normal adult muscle and embryonic muscle (E17) were used as negative and positive controls, respectively. The expression of GAPDH was analyzed as a loading control. The brownish color represents the positive immunostaining reaction product, and the blue color is hematoxylin counterstaining. Bars, 20 µm (A,B) and 30 µm (C,D).





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