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Fig. 4. UVC-radiation alters PML subcellular levels and its interaction with Mdm2. SaOS-2 cells were treated with MG132 (10 µM) or were radiated with UVC and incubated for 6 hours. (A) Soluble and insoluble PML fractions were analysed by immunoblotting. (B) Cellular lysates were immunoprecipitated with Mdm2 antibodies followed by immunoblotting as indicated.





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