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Fig. 9. Dose-dependent aggregation of FN-null CHO-
5 cells. CHO-5
cells express high levels of 5 integrin but do not express N-cadherin
or secrete FN. Cells were cultured in hanging drops either in the absence of
FN (A) or in 3 (B), 30 (C), 100 (D) or 300 (E) µg/ml rat plasma FN. Note
the dose-dependent aggregation and compaction of CHO-5 cells in
response to the addition of exogenous FN. Bar, 0.5 mm.
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