Fig. 3. (A) Numbers of donor myoblasts in irradiated and contralateral (protected) TA muscles in mdx host mice subjected to WBI with one leg protected. MTT was performed 24 hours after WBI and muscles sampled at 1 hour, 24 hours and 72 hours after MTT. Schematics of the irradiation treatment of host mice (see Fig. 1) are indicated in the top right-hand corner. Bars indicate s.d. * P<0.05, **P<0.005 (untreated to treated samples) using ANOVA; d and dd indicate significances of P<0.05 or P<0.005, respectively, between treatment groups at each time point using ANOVA (n=6 unless otherwise stated). (B) Numbers of donor myoblasts in irradiated and contralateral (protected) TA muscles in mdx host mice subjected to local irradiation of one leg only. MTT was performed 24 hours after irradiation and muscles sampled at 1 hour, 24 hours and 72 hours after MTT. Bars indicate s.d. *P<0.05, **P<0.005 (untreated to treated samples) using ANOVA; d and dd indicate significances of P<0.05 or P<0.005, respectively, between treatment groups at each time point using ANOVA (n=6 unless otherwise stated).

Return to article