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Fig. 7. Increased nucleocytoplasmic shuttling of p120 after deletion of Arm repeat 10. E-cadherin-positive A431 cells were transduced with p120-3A, p120-3A
Arm8 or p120-3A
Arm10 and their distribution examined by immunofluorescence p120-3A localizes to the adherens junctions of A431 cell before and after LMB treatment (A and B). The arm 8 deletion mutant localizes to the adherens junctions, the cytoplasm and the nucleus both before and after LMB treatment (C and D). The Arm 10 deletion mutant localizes to the adherens junctions before LMB treatment (E) and prominently to the nucleus after LMB treatment (F).