Fig. 3. LFA-1-mediated migration of T cells on ICAM-1. Time-lapse video microscopy (x40 magnification) of a primary human T cell in contact with immobilized ICAM-1. The time in seconds after the first contact with ICAM-1 is depicted in each frame: initial contact (time=0), T-cell polarization (time=60-160 seconds) and migration (time=200 seconds) (Smith et al., 2003). Data reproduced with kind permission of Andrew Smith, Cancer Research, UK.

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