Fig. 6. Identification of the chromosomal component in the protruding arm phenotype. Analysis by FISH at 72 hours after the addition of Topo II dsRNA using the following probes. (A) Euchromatic chromosome 3 probe (BACH47K04); (B) Euchromatic chromosome X probe (BACH47E07). In A and B, arrowheads indicate FISH signal in protruding arm. (C) Euchromatic chromosome 2 probe (BACHN09); (D) Heterochromatic chromosome X probe (359 satellite); large arrowhead points to extended FISH signal in protruding arm; small arrowhead points to condensed FISH signal in metaphase plate. In all merged images, the probe is green and the DNA is red. Scale bar: 5 µm.

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