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Fig. 3. A model for entry into mitosis based on work in fission yeast and Xenopus. Work in Xenopus suggests that Polo kinase might be required for activation of Cdc5 and entry into mitosis; however, work in fission yeast suggests that Polo kinase might not be required for entry into mitosis (see text). Kinases are shown in yellow and phosphatases are shown in pink.





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