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A guide to nuclear receptors

Nuclear receptors are ligand-activated transcription factors that bind to hormones such as oestrogen and progesterone, as well as a variety of other ligands, including vitamin D3 and prostaglandin J2. They form a large gene family — C. elegans alone has >270 members — and many have no known ligand. In Cell Science at a Glance, Marc Robinson-Rechavi and co-workers provide a brief introduction to these receptors, including a phylogenetic analysis of the known family members and a summary of their mode of action (see p. 585 + poster).

Related articles in JCS:

The nuclear receptor superfamily

Marc Robinson-Rechavi, Hector Escriva Garcia, and Vincent Laudet
JCS 2003 116: 585-586. [Full Text]  

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in JCS Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Search for Related Content