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Fig. 6. Possible NF-{kappa}B-like binding sites within the VEGF 5'-promoter region. Sequences that differ at the level of one or two positions from the decameric {kappa}B-like binding sites (5'-HGGARNYYCC-3', where H indicates A, C, or T; R indicates A or G; Y indicates C or T; N indicates any nucleotide) and NF-{kappa}B-like consensus sequence (5'-GGGRNNYYCC-3', where R indicates A or G, Y indicates C or T, and N indicates any nucleotide) in the VEGF promoter (Tischer et al., 1991) are highlighted (bold and underlined).





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