spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 1. A novel post-phosphorylation regulatory mechanism in phosphorylation signaling. Phosphorylation of proteins by proline-directed kinases (e.g. CDKs, MAPKs, GSK-3ß) creates binding sites for the prolyl-isomerase Pin1 (1st step). Subsequent prolyl-isomerization by Pin1 induces conformational changes and thereby regulates the function of target proteins (2nd step).





Right arrow Return to article