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Fig. 1. Relocalization of 
SpII
* to nuclear foci following treatment
of normal cells with 8-MOP plus UVA light. The localization of
SpII* in the nucleus of undamaged normal human lymphoblastoid
cells or lymphoblastoid cells treated with 8-MOP plus UVA light (6 kJ
m-2) was examined by immunofluorescence with purified monoclonal
anti--spectrin antibody. Counterstaining for the DNA-specific dye DAPI
is shown in the middle panels. In the bottom panels, the fluorescent signal
for DAPI was overlaid on that for anti--spectrin. Cells were fixed for
staining 15 hours after treatment with 8-MOP plus UVA.
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