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Fig. 12. Cross-sectional area of fiber cells in wild-type and {alpha}A–/– mouse lenses. Lens slices were cut in the equatorial plane and stained with an antibody to MIP (AQP0) to visualize fiber cell membranes. The distance from the center of the lens was 300 µm. The organization of the fiber cells in these equatorial sections of wild-type and {alpha}A–/– mice is different, and the membranes of the wild-type lens fiber cells appear smoother than those of the {alpha}A–/–. Variation in the cross-sectional areas of the different fiber cells was noted for both wild-type and {alpha}A–/– cells. However, the distribution of the cross-sectional areas of the fiber cells was similar in wild-type and {alpha}A–/– lenses. Bar, 10 µM (A,B).





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