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Fig. 5. BrdU labeling index in the lens epithelial wholemounts at successive times
after BrdU injection. Seven-day-old wild-type or
A/ mice were injected with BrdU and
wholemounts were fixed at successive times after the BrdU injection. The BrdU
labeling index was determined at 1, 3, 8, 16 and 24 hours, and 2, 3 and 5 days
after the BrdU injection. Four lenses were used at each time point. Note that
the labeling index of the
A/ wholemount lagged
the labeling index of the wild-type between 16 hours and 5 days.