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Fig. 6. (A,B) Time course of the relative fluorescence intensities (unbroken line, cytosol; broken line, nucleus) of the Ca2+ indicators in two single HaCaT cells after stimulation with CRF (A, 10-7 M) and URC (B, 10-7 M). (C) Dose-dependent frequency of the oscillations in HaCaT-cells after stimulation with URC (mean and s.d.). Number of cells recorded (n) is shown in the respective columns. (D) Dose-dependent numbers of HaCaT cells with oscillations after stimulation with URC (percentage of total number of cells recorded). Number of cells recorded with oscillations (n) is shown in the respective columns.





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