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Fig. 5. Modulation of IB1/JIP-1 regulates apoptosis in isolated rat islets induced by cytokines. Apoptosis rate in dispersed rat islet cells infected with the different adenovirus constructs and treated or not with cytokines (IL-1ß, TNF-{alpha} and IFN-{gamma}). Columns represent mean ± s.e.m. of three independent experiments performed in duplicate. *P<0.05; **, °°or §§ P<0.01; ***P<0.001.





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