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Fig. 5. DNA damage induces centrosome amplification but does not relocate hPARP-3. HeLa HC1 cells expressing GFP-centrin (green) were immunostained with an anti-hPARP-3 (red) antibody 120 hours after treatment with 1 mM MNU (A-C) or with 1 mM hydrogen peroxide (D-F). Examples of monopolar and multipolar spindles are shown. Bars, 10 µm.





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