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Journal of Cell Science 116, e905 (2003)
Copyright © 2003 The Company of Biologists Limited

In this issue

Picturing tooth development


Tooth development is a good example of a morphogenetic process driven by interactions between ectoderm and underlying mesenchyme. The two tissues release numerous paracrine signalling molecules, which in turn regulate expression of a host of transcription factors that define the developmental stage of the target tissue. In Cell Science at a Glance, Irma Thesleff surveys the various genes involved, the stages at which they act and the developmental changes that occur as a consequence (see p. 1647 + poster).


Related articles in JCS:

Epithelial-mesenchymal signalling regulating tooth morphogenesis
Irma Thesleff
JCS 2003 116: 1647-1648. [Full Text]  




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