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Fig. 1. Cell trafficking from the BM to the skeletal muscle 3 weeks after lethal irradiation and BMT. Detection via FACS analysis of donor-derived CD45.2⁺ cells within the MP and SP cell populations in the BM (A-D) and the skeletal muscle (E-H) of recipient females. BM cells stained with 5 µg ml^-1 Hoechst in the presence (A) or absence (B) of verapamil. Over 99% of BM MP cells (C) and SP cells (D) are CD45.2⁺ or of donor origin. Skeletal muscle mononuclear cells stained with 12.5 µg ml^-1 Hoechst dye in the presence (E) or absence (F) of verapamil. Approximately 18% of muscle MP cells (G) are CD45.2⁺ donor-derived, whereas all muscle SP cells are CD45.2^- (H).

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