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Fig. 2. Effect of BDM on Listeria and InlA-coated beads internalization. Entry of wild-type L. monocytogenes into human Caco-2 cells and of L. innocua expressing InlA and of InlA-coated beads into L2071 fibroblasts expressing human E-cadherin, in the presence of 10 mM or 50 mM BDM was evaluated and compared with entry in untreated cells. Vero cells were infected with wild-type L. monocytogenes and L. monocytogenes {Delta}inlA in the absence or presence of BDM and the entry levels were determined. Entry to untreated cells has been normalized to 100 and the levels of entry in cells treated with BDM are expressed as relative values. Results are means±SD from three independent experiments, each done in triplicate.





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