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Fig. 6. Reduced transglutaminase 1 (TG1) activity in CTSD-deficient mice. TG1 enzymatic activity was determined in epidermal lysates from wild type, heterozygous and CTSD-deficient mice by an in-vitro assay using dimethylcasein and [1,4(n)-3H] putrescine as substrates. Results of three experiments performed in triplicate are shown (mean±s.e.m.).





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