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Fig. 3. Amyloid fibrils of recombinant HET-s(157-289). (A-D) Electron microscopy of HET-s(157-289) aggregates. (B,C) Tightly compacted fibrils and more loosely organized bundles fringing out into individual fibrils. (D) The well-ordered lateral association of individual fibrils. Scale bars, 10 µm (A), 500 nm (B), 200 nm (C), 100 nm (D). (E) light microscopy of HET-s(157-289) fibrils. Scale bar, 10 µm. (F) Fluorescence microscopy of HET-s(157-289) stained with Congo red. Scale bar, 10 µm.