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Fig. 2. Mitochondrion transported by anterograde and retrograde transport dock in the middle of the gap between stationary mitochondria. (A) Examples of mitochondria pausing during fast axonal transport. (B) Normalized distribution of mitochondrial stops relative to the two closest stationary mitochondria (n=58 stopping events). (C) Histogram analysis of the relative position of the stops in relation to the two closest mitochondria (n=58 stopping events). (D) Circular histogram of stopping events. Line with arrowhead shows the sum (R) and net angle of the vectors. (E) Cumulative probabilities of the vector sums of 58 random events generated by Monte Carlo simulation. From this, we estimate the probability of the observed clustering shown in (C) to be P<0.036.





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